Parvasi Newspaper Punjabi Newspaper
Steps Toward Informed and Healthy Relationship
In today’s era of personalized medicine and informed decision-making, genetic health has emerged as a critical factor in couple relationships—especially for those planning for marriage and to start a family. While love, communication, and shared values remain the cornerstones of a successful partnership, understanding each partner’s genetic background can play a vital role in ensuring longterm health and harmony. Genetic compatibility not only helps couples assess the risk of passing on inherited conditions to their children but also fosters deeper conversations about future planning, medical preparedness, and mutual support.
As science continues to unveil the intricate links between genetics and human behaviour, the integration of genetic health into relationships empowers couples to make choices that reflect both emotional and biological compatibility.
As more couples prioritize health and long-term compatibility in their relationships, genetic prescreening has become an increasingly important step in family planning and romantic decision making. This screening can help identify potential genetic risks for future offspring, evaluate biological compatibility, and support shared decisions about reproductive health. Here’s a detailed look at the steps involved in the process.
Step 1: Pre-Test Counselling : Before any testing begins, couples usually meet with a genetic counsellor or healthcare provider.
This session includes : Discussing family medical histories
Understanding the purpose and limitations of genetic testing/Exploring the ethical, emotional, and reproductive implications of the results
Determining which specific tests are relevant
(e.g., carrier screening, ancestry-linked disorders)
Step 2 : Sample Collection : Genetic testing typically requires 2-3 ml blood sample in Heparin or EDTA vial.
Step 3 : Genetic Analysis : The lab examines the DNA samples for a range of genetic infectious and blood transmitted diseases.
Premarital screening test includes the following:
• Complete blood count (CBC)
• Blood group (ABO & Rh typing)
• Hb Variants testing (Thalassemia, Sickle cell)
• G6PD
• Sexually transmitted diseases
• HIV
• Hepatitis B
• Hepatitis C
• Syphilis
• Other STDs (i.e gonorrhea, Chlamydia …)
Other testing might include:
• Male and Female fertility testing (Hormone testing, semen analysis, ovarian function).
• Karyotyping
Advanced sequencing technologies, such as whole exome sequencing (WES) or targeted gene panels, may be used depending on the test scope.
Step 4 : Results Interpretation
Once results are ready, the couple returns for post-test counseling to:
Review findings and understand what they mean
Assess any genetic risks to potential offspring
Explore reproductive options (e.g., IVF with genetic screening, egg/sperm donors, adoption)
Address any psychological or relational concerns
Step 5: Decision-Making and Planning
Based on the results and counselling, couples can make informed decisions regarding:
Family planning and prenatal options
Lifestyle and health precautions
Open communication about potential challenges
In some cultures or communities, these results may also impact social or religious decisions around marriage.
Why Consider Genetic Pre-Screening?
Informed family planning : Early detection of preventable conditions
Better compatibility understanding (in optional behavioural gene testing)
Peace of mind
Limitations to Keep in Mind : Not all genetic risks can be screened.
Results don’t guarantee future health outcomes.
Emotional impact may vary based on results.
Genetics is only one part of compatibility—values, communication, and emotional health remain crucial.
Conclusion : Genetic pre-screening is a powerful tool for couples looking to build a healthy future together. By following a structured, ethical, and well-informed approach, couples can make proactive decisions that align with their shared goals and values.
